2. GPCR/G Protein Neuronal Signaling
  3. mAChR
  4. Timepidium bromide

Timepidium bromide  (Synonyms: Sesden; SA504)

目录号: HY-U00184
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摩尔计算器

Timepidium bromide (Sesden; SA504) 是一种抗胆碱剂。

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Timepidium bromide Chemical Structure

Timepidium bromide Chemical Structure

CAS No. : 35035-05-3

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Timepidium bromide 相关抗体

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  • 生物活性

  • 实验参考方法

  • 纯度 & 产品资料

  • 参考文献

生物活性

Timepidium bromide (Sesden; SA504) is an anticholinergic agent.

IC50 & Target

Cholinergic[1]
体内研究
(In Vivo)

Effects of Timepidium bromide (TB), acetylcholine (ACh) and neostigmine (Neost) on gastric and duodenal blood flow distribution are studied by the use of 131I-labeled macroaggregated human serum albumin (MAA) in rabbits. In normal rabbits, gastric blood flow is found to be uneven in various regions of the stomach: anterior corpus (50% of total gastric blood flow) greater than posterior corpus (40%) greater than pyloric antrum (7%). Intravenous administration of Timepidium bromide (200 μg/kg) to normal rabbits produces a slight increase in total gastric blood flow, but the increase in the mucosal layer of the pyloric antrum is considerable[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

400.40

Formula

C17H22BrNOS2
CAS 号
中文名称

噻哌溴铵
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献
Animal Administration
[1]

Rabbits[1]
Timepidium bromide (200 μg/kg) is injected into the femoral vein 5 min prior to 131I-MAA. To evaluate the effects of Timepidium bromide on gastric and duodenal blood flow in cholinergic drug-treated animals, Timepidium bromide is administered in a dose of 200 μg/kg through the femoral vein 3 min before ACh or 5 min after Neost. 131I-MAA is given into the left ventricle of the animals 2 min after ACh and 10 min after Neost.

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
参考文献

Timepidium bromide 相关分类

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Keywords:

Timepidium35035-05-3Sesden SA504噻哌溴铵SA504SA 504SA-504mAChRMuscarinic acetylcholine receptorInhibitorinhibitorinhibit

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