2. GPCR/G Protein
  3. Prostaglandin Receptor
  4. Tiaprost

Tiaprost  (Synonyms: 噻前列素; Iliren)

目录号: HY-111478 纯度: ≥98.0%
COA 产品使用指南

摩尔计算器

Tiaprost 是一种前列腺素 F2α (PGF2α) 类似物。

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Tiaprost Chemical Structure

Tiaprost Chemical Structure

CAS No. : 71116-82-0

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规格 价格 是否有货 数量
1 mg (25.22 mM * 100 μL in Ethanol) ￥1382
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Tiaprost 相关抗体

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DP EP FP IP TXA2/TP TXB2

  • 生物活性

  • 实验参考方法

  • 纯度 & 产品资料

  • 参考文献

生物活性

Tiaprost is a prostaglandin F2α (PGF2α) analogue.

IC50 & Target[1]

PGF2α

 

体内研究
(In Vivo)

Plasma progesterone levels decrease sharply within 12 hours after the initial treatment with Tiaprost and within 24 hours reach levels at about 3.18 nM (1 ng/mL). Over the following days, progesterone levels remain either slightly above (cows 1, 3, 5 and 6) or below (cow 2) 3.18 nM. In cow 4, levels remain for 17 days above 3.18 nM and drop below this level thereafter. At term, all cows show the lowest recorded progesterone levels (1 to 2 nM). Repeated luteolytic treatments with Tiaprost (cows 1 and 2) or estradio1 benzoate (cow 3) has no further influence on individual progesterone levels. Treatment with progesterone-releasing intravaginal device (PRID) does not significantly elevate progesterone plasma levels. Total estrogens in plasma remained in general unchanged[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

396.50

Formula

C20H28O6S
CAS 号
性状

液体

颜色

Colorless to light yellow

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Solution, -20°C, 2 years
纯度 & 产品资料

纯度: ≥98.0%

COA (293 KB)

产品使用指南 (1538 KB)
参考文献
Animal Administration
[1]

Cows[1]
Six healthy dairy cows of the German Black Pied breed, pregnant for 190 to 266 days, are treated initially with 0.75 mg of the PGF2α analog Tiaprost SC (treatment day=day 0). All animals are moved to the department’s large animal hospital 5 to 20 days before treatment commenced; they are kept in stanchions and fed. All animals are examined clinically daily and rectally as well as vaginally at two- to six-day intervals[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
参考文献

Tiaprost 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tiaprost71116-82-0IlirenProstaglandin ReceptorInhibitorinhibitorinhibit

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