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Trombodipine  (Synonyms: PCA-4230)

目录号: HY-19052
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摩尔计算器

Trombodipine 是一种抗血栓剂。

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Trombodipine Chemical Structure

Trombodipine Chemical Structure

CAS No. : 113658-85-8

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Trombodipine 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 实验参考方法

  • 纯度 & 产品资料

  • 参考文献

生物活性

Trombodipine is an antithrombotic agent.

体外研究
(In Vitro)

Trombodipine is an antithrombotic agent. Exposure to 50 μM Trombodipine reveals an important stasis of growth. The percentage of inhibition exerted by 1 μM Trombodipine on day 3, 5 and 7 of the growth curve is 22.0±4.5, 32.0±3.0 and 29.4±6.0%, respectively (P<0.05). The inhibitory effect of Trombodipine on cell proliferation is reversible and after removal of Trombodipine the proliferation of the cells is resumed[1]. Addition of Trombodipine reduces cell number in a dose-dependent manner over a period of 4 to 6 days in culture. When compare to control cultures at the latest time points investigated, 5 μM Trombodipine decreases the number of E19P cells and human VSMCs by 25 and 21%, respectively, whereas 50 μM Trombodipine reduces E19P and human VSMC number by 85 and 74%, respectively[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Trombodipine 相关抗体:
分子量

448.49

Formula

C21H24N2O7S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献
Cell Assay
[1]

To estimate the proportions of cells in different phases of the cell cycle, cellular DNA contents are measured by flow cytometry. Cells are plated, allowed to attach overnight, and placed in serum-free medium for 48 h. Trombodipine (50 μM) is added at selected points during serum repletion. At the specified times after serum addition, the cells are harvested by trypsinization, washed with PBS, pelleted and resuspended in PBS containing 0.6% Nonidet P-40 and 100 μg/mL propidium iodide (PI). Flow cytometric analyses are done with a FACScan flow cytometer[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
参考文献

Trombodipine 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

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Keywords:

Trombodipine113658-85-8PCA-4230PCA4230PCA 4230OthersInhibitorinhibitorinhibit

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