2. GPCR/G Protein Neuronal Signaling
  3. Cholecystokinin Receptor
  4. A-70874

A-70874 是不含酪氨酸残基的胆囊收缩素四肽 (30-33) (CCK-4) 类似物，A-70874 是刺激胰腺淀粉酶释放的激动剂、和刺激胰腺中磷酸肌醇分解的部分激动剂。A-70874 对豚鼠胰腺的 CCK 受体的 IC50 为 4.9 nM。胆囊收缩素 (CCK) 受体被分为 CCK-A (消化道) 和 CCK-B (脑)。A-70874 对 CCK-B/胃泌素受体的亲和力为 1.6 μM。

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A-70874 Chemical Structure

A-70874 Chemical Structure

CAS No. : 131449-37-1

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A-70874 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

A-70874 is a tyrosine-free tetrapeptide analog of cholecystokinin (30-33) (CCK-4). A-70874 is an agonist that stimulates pancreatic amylase release and a partial agonist that stimulates pancreatic phosphoinositide decomposition. A-70874 has an IC50 of 4.9 nM for the guinea pig pancreatic CCK receptor. Cholecystokinin (CCK) receptors are divided into CCK-A (digestive tract) and CCK-B (brain). A-70874 has an affinity of 1.6 μM for the CCK-B/gastrin receptor[1].

分子量

853.96

Formula

C45H55N7O10
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

A-70874 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

A-70874131449-37-1A70874A 70874Cholecystokinin ReceptorCCK ReceptorInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-129516
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