1. GPCR/G Protein
  2. Adenosine Receptor
  3. A1/A3 AR antagonist 3

A1/A3 AR antagonist 3 是一种 A1R/A3R 双重拮抗剂,在低微摩尔到低纳摩尔范围内具有高亲和力。A1/A3 AR antagonist 3 可用于慢性心脏病的研究。

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A1/A3 AR antagonist 3 Chemical Structure

A1/A3 AR antagonist 3 Chemical Structure

CAS No. : 2665804-57-7

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

A1/A3 AR antagonist 3 is an A1R/A3R dual antagonist with high affinity at low-micromolar to low-nanomolar. A1/A3 AR antagonist 3 can be used for the research of chronic heart diseases[1].

IC50 & Target

pKd: 8.25 (A1R); 7.87 (A3R)[1].
pKi: 8.36 (A1R); 8.01 (A3R)[1].

体外研究
(In Vitro)

A1/A3 AR antagonist 3 (A17) 对 A1R 和 A3R 具有结合亲和力,pKd 值分别为 8.25 和 7.87[1]
A1/A3 AR antagonist 3 对 A1R 和 A3R 具有结合亲和力,pKi 值分别为 8.36 和 8.01[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

401.42

Formula

C22H19N5O3

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

A1/A3 AR antagonist 3 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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