2. GPCR/G Protein Neuronal Signaling
  3. Dopamine Receptor
  4. A68930

A68930 作为 dopamine D1 receptor 激动剂，可用于支气管扩张的研究。

在相同的摩尔浓度下，化合物盐形式与游离形式有相同的生物活性，但盐形式 A68930 hydrochloride 通常具有更好的水溶性和稳定性。

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A68930 Chemical Structure

A68930 Chemical Structure

CAS No. : 130465-45-1

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A68930 的其他形式现货产品:

Customer Review

Other Forms of A68930:

A68930 相关抗体

Top Publications Citing Use of Products

查看 Dopamine Receptor 亚型特异性产品:

查看所有亚型
Dopamine Receptor D1 Receptor D2 Receptor D3 Receptor D4 Receptor D5 Receptor

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

A68930, as a dopamine D1 receptor agonist, can be used for the research of bronchiectasis[1].

IC50 & Target

D1 Receptor

 

体外研究
(In Vitro)

A68930 (1 μM; 5-60 minutes; 16HBE14o- or NCI-H292 cells) significantly increases phosphorylation of cAMP response element binding (CREB) protein[1].
A68930 (1 μM; 48 hours; NCI-H292 cells) induces MUC5AC mRNA expression and increases the mRNA data of MUC5AC and MUC5AC protein expression[1].
A68930 (1 μM; 20 minutes; NCI-H292 cells) significantly increases intracellular cAMP levels[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

A68930 相关抗体:

Western Blot Analysis[1]

Cell Line: 16HBE14o- or NCI-H292 cells
Concentration: 1 μM
Incubation Time: 5~60 minutes
Result: Significantly increased phosphorylation of CREB.

RT-PCR[1]

Cell Line: NCI-H292 cells
Concentration: 1 μM
Incubation Time: 48 hours
Result: Induced MUC5AC mRNA expression.

Immunofluorescence[1]

Cell Line: NCI-H292 cells
Concentration: 1 μM
Incubation Time: 48 hours
Result: The mRNA data of MUC5AC, MUC5AC protein expression were increased.
分子量

271.31

Formula

C16H17NO3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

A68930 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

A68930130465-45-1A 68930A-68930Dopamine ReceptorbronchiectasisMUC5ACNCI-H292CREBcAMPInhibitorinhibitorinhibit

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目录号：
HY-120687
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