2. Cell Cycle/DNA Damage Apoptosis Metabolic Enzyme/Protease Cytoskeleton Anti-infection
  3. HPV Microtubule/Tubulin Endogenous Metabolite Apoptosis
  4. Sabizabulin hydrochloride

Sabizabulin hydrochloride  (Synonyms: VERU-111 hydrochloride; ABI-231 hydrochloride)

目录号: HY-120599A
产品使用指南 技术支持

Sabizabulin hydrochloride是一种有效的口服生物利用度的微管抑制剂，具有与秋水仙碱结合位点相互作用的活性。Sabizabulin hydrochloride显示出在黑色素瘤和前列腺癌细胞系中的平均IC50为5.2 nM，显著抑制黑色素瘤肿瘤的生长。Sabizabulin hydrochloride的药理筛选表明其具有低潜在副作用的风险。

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Sabizabulin hydrochloride Chemical Structure

Sabizabulin hydrochloride Chemical Structure

CAS No. : 2635953-17-0

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规格 是否有货
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Sabizabulin hydrochloride 的其他形式现货产品:

Other Forms of Sabizabulin hydrochloride:

Sabizabulin hydrochloride 相关抗体

Top Publications Citing Use of Products

MCE 顾客使用本产品发表的 2 篇科研文献

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Sabizabulin hydrochloride is a potent orally bioavailable microtubule inhibitor with activity that interacts with the colchicine binding site. Sabizabulin hydrochloride demonstrated significant inhibition of melanoma tumor growth with an average IC50 of 5.2 nM in melanoma and prostate cancer cell lines. Pharmacological screening of Sabizabulin hydrochloride shows it has a low risk of potential side effects[1].

分子量

413.85

Formula

C21H20ClN3O4
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Sabizabulin hydrochloride 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Sabizabulin2635953-17-0VERU-111ABI-231VERU111VERU 111ABI231ABI 231HPVMicrotubule/TubulinEndogenous MetaboliteApoptosisHuman papillomavirusInhibitorinhibitorinhibit

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