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  3. ABI-231 hydrochloride

ABI-231 hydrochloride是一种有效的口服生物利用度的微管抑制剂,具有与秋水仙碱结合位点相互作用的活性。ABI-231 hydrochloride显示出在黑色素瘤和前列腺癌细胞系中的平均IC50为5.2 nM,显著抑制黑色素瘤肿瘤的生长。ABI-231 hydrochloride的药理筛选表明其具有低潜在副作用的风险。

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ABI-231 hydrochloride Chemical Structure

ABI-231 hydrochloride Chemical Structure

CAS No. : 2635953-17-0

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ABI-231 hydrochloride 的其他形式现货产品:

Other Forms of ABI-231 hydrochloride:

MCE 顾客使用本产品发表的 2 篇科研文献

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

ABI-231 hydrochloride is a potent orally bioavailable microtubule inhibitor with activity that interacts with the colchicine binding site. ABI-231 hydrochloride demonstrated significant inhibition of melanoma tumor growth with an average IC50 of 5.2 nM in melanoma and prostate cancer cell lines. Pharmacological screening of ABI-231 hydrochloride shows it has a low risk of potential side effects[1].

分子量

413.85

Formula

C21H20ClN3O4

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

ABI-231 hydrochloride 相关分类

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  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
ABI-231 hydrochloride
目录号:
HY-120599A
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