1. Apoptosis
  2. Apoptosis
  3. Ac-​IETD-​CHO

Ac-?IETD-?CHO 是一种有效的、可逆的 granzyme Bcaspase-8 抑制剂。 Ac-?IETD-?CHO 抑制 Fas 介导的细胞凋亡 (Apoptosis)、出血和肝衰竭。Ac-?IETD-?CHO 还可抑制细胞毒性 T 淋巴细胞诱导的细胞死亡。

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Custom Peptide Synthesis

Ac-​IETD-​CHO Chemical Structure

Ac-​IETD-​CHO Chemical Structure

CAS No. : 191338-86-0

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Ac- IETD- CHO is a potent, reversible inhibitor of granzyme B and caspase-8. Ac- IETD- CHO inhibits Fas-mediated apoptotic cell death, hemorrhage, and liver failure. Ac- IETD- CHO also inhibits cytotoxic T lymphocytes induced cell death[1][2].

分子量

502.52

Formula

C21H34N4O10

CAS 号
Sequence

Ac-Ile-Glu-Thr-Asp-CHO

Sequence Shortening

Ac-​IETD-​CHO

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • 稀释计算器

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Ac-​IETD-​CHO
目录号:
HY-113963
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