2. Antibody-drug Conjugate/ADC Related PROTAC
  3. ADC Linker PROTAC Linkers
  4. AEEA-AEEA

AEEA-AEEA 是可降解 (cleavable) 的 ADC linker，用于合成抗体偶联活性分子 (ADCs)。AEEA-AEEA 也是一个基于 PEG 的 PROTAC linker，可用于合成 PROTAC。

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AEEA-AEEA Chemical Structure

AEEA-AEEA Chemical Structure

CAS No. : 1143516-05-5

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     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

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1 g ￥165
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5 g ￥659
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Customer Review

AEEA-AEEA 相关抗体

Top Publications Citing Use of Products

查看 ADC Linker 亚型特异性产品:

查看所有亚型
Cleavable Linker Non-cleavable Linker Acid Cleavable Linker Disulfide Cleavable Linker Protease Cleavable Linker Glycosidase Cleavable Linker Phosphatase Cleavable Linker

查看 PROTAC Linkers 亚型特异性产品:

查看所有亚型
PEG Linkers Alkyl-Chain Linkers Alkyl/ether Linkers

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

AEEA-AEEA is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). AEEA-AEEA is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

IC50 & Target

Cleavable Linker

 

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

AEEA-AEEA 相关抗体:
分子量

308.33

Formula

C12H24N2O7
CAS 号
性状

固体

颜色

White to off-white

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

溶解性数据
细胞实验： 

DMSO 中的溶解度 : < 1 mg/mL (insoluble or slightly soluble)

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只
由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料

纯度: 99.12%

COA (276 KB)

产品使用指南 (1538 KB)
参考文献

AEEA-AEEA 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AEEA-AEEA1143516-05-5ADC LinkerPROTAC LinkersAntibody-drug conjugates linkerInhibitorinhibitorinhibit

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产品名称：
AEEA-AEEA
目录号：
HY-W125504
需求量：

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