2. Immunology/Inflammation
  3. Interleukin Related
  4. Afasevikumab

Afasevikumab  (Synonyms: 阿法库单抗; RG 7624; RO 5553110; NI-1401)

目录号: HY-P99424 纯度: 95%
COA

摩尔计算器

Afasevikumab (RG 7624; RO 5553110; NI-1401) 是一种全人单克隆 IgG1κ 抗体，可中和 IL-17A 和 IL-17F。Afasevikumab 具有抗炎活性。

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CAS No. : 1589503-30-9

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     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 价格 是否有货 数量
1 mg ￥3000
In-stock
5 mg ￥9000
In-stock
10 mg   询价  
50 mg   询价  

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Customer Review

Afasevikumab 相关抗体

Top Publications Citing Use of Products

查看 Interleukin Related 亚型特异性产品:

查看所有亚型
IL-1 IL-2 IL-3 IL-4 IL-5 IL-6 IL-8 IL-10 IL-12 IL-13 IL-15 IL-17 IL-23 IL-7 IL-33 IL-22

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Afasevikumab (RG 7624; RO 5553110; NI-1401) is a fully human monoclonal IgG1κ antibody neutralizing both IL-17A and IL-17F. Afasevikumab has anti-inflammatory activities[1].

同型

Human IgG1 kappa
推荐同型对照抗体
体外研究
(In Vitro)

Afasevikumab 由 N 末端 IL-17F 特异性部分、结合 IL-17A 和 IL-17F 的 a-C 末端部分以及结合人血清白蛋白的中心部分组成[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Afasevikumab 相关抗体:
CAS 号
性状

液体

颜色

Colorless to light yellow

中文名称

阿法库单抗
运输条件

Shipping with dry ice.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • Human IgG1 kappa
Biological Activity
  • Loaded IL-17A Protein, Human (HEK293, His, HY-P70527) on AHC2 biosensor, can bind Afasevikumab with an affinity constant of <1.000E-11 M as determined in BLI assay.
纯度 & 产品资料
参考文献

Afasevikumab 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Afasevikumab1589503-30-9RG 7624 RO 5553110 NI-1401阿法库单抗RG7624RG-7624RO5553110RO 5553110RO-5553110NI1401NI 1401NI-1401Interleukin RelatedILhuman monoclonal IgG1κ antibodyIL-17AIL-17Fanti-inflammatory activitiesInhibitorinhibitorinhibit

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