2. Metabolic Enzyme/Protease
  3. Aldose Reductase
  4. AKR1C3-IN-12

AKR1C3-IN-12 (compound 2j) 是一种醛酮还原酶 1C3 (AKR1C3) 抑制剂，IC50 为 27 nM。AKR1C3-IN-12 可增强吉西他滨和顺铂对膀胱癌的疗效。

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AKR1C3-IN-12 Chemical Structure

AKR1C3-IN-12 Chemical Structure

CAS No. : 891075-67-5

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AKR1C3-IN-12 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

AKR1C3-IN-12 (compound 2j) is an aldo-keto reductase 1C3 (AKR1C3) inhibitor with an IC50 of 27 nM. AKR1C3-IN-12 enhances the efficacy of Gemcitabine and Cisplatin in bladder cancer[1].

IC50 & Target

IC50: 27 nM (AKR1C3)[1]
分子量

294.30

Formula

C17H14N2O3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

AKR1C3-IN-12 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AKR1C3-IN-12891075-67-5Aldose ReductaseAKR1C3 inhibitorbladder cancerELK1Inhibitorinhibitorinhibit

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