2. PI3K/Akt/mTOR
  3. Akt
  4. AKT-IN-10

AKT-IN-10 是一种有效的 AKT 抑制剂。蛋白激酶 B (PKB，也称为 AKT) 是细胞中 PI3K/AKT/mTOR 信号传导的核心，其功能对细胞生长、存活、分化和代谢很重要。AKT-IN-10 具有研究乳腺癌和前列腺癌的潜力 (摘自专利 WO2021185238A1，化合物 4)。

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AKT-IN-10 Chemical Structure

AKT-IN-10 Chemical Structure

CAS No. : 2709045-56-5

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AKT-IN-10 相关抗体

Top Publications Citing Use of Products

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Akt Akt1 Akt2 Akt3

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

AKT-IN-10 is a potent inhibitor of AKT. Protein kinase B (PKB, also known as AKT) is central to PI3K/AKT/mTOR signaling in cells, and its function is important for cell growth, survival, differentiation and metabolism. AKT-IN-10 has the potential for the research of breast and prostate cancer (extracted from patent WO2021185238A1, compound 4)[1].

IC50 & Target

AKT[1]
分子量

484.03

Formula

C26H34ClN5O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

AKT-IN-10 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AKT-IN-102709045-56-5AktPKBProtein kinase BAKTPI3KmTORgrowthsurvivaldifferentiationmetabolismbreastprostate cancerInhibitorinhibitorinhibit

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目录号：
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