2. Anti-infection Metabolic Enzyme/Protease
  3. HCV Protease
  4. AL-611

AL-611 是一种 HCV NS5B 聚合酶抑制剂（EC50 = 5 nM）。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

我们将采用定制合成服务的方式为您快速提供所需产品和技术服务

AL-611 Chemical Structure

AL-611 Chemical Structure

CAS No. : 2481279-61-0

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 价格 是否有货
1 mg ￥6000
询问价格 & 货期
5 mg 现货 询问价格 & 货期
10 mg 现货 询问价格 & 货期

* Please select Quantity before adding items.

Customer Review

Other Forms of AL-611:

AL-611 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

AL-611 is an HCV NS5B polymerase inhibitor (EC50 = 5 nM).

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
A549 CC50
> 100 μM
Compound: 40
Cytotoxicity against human A549 cells incubated for 8 days by cellTiter-Glo assay
Cytotoxicity against human A549 cells incubated for 8 days by cellTiter-Glo assay
[PMID: 32816483]
HeLa CC50
> 100 μM
Compound: 40
Cytotoxicity against human HeLa cells incubated for 8 days by cellTiter-Glo assay
Cytotoxicity against human HeLa cells incubated for 8 days by cellTiter-Glo assay
[PMID: 32816483]
HepG2 CC50
> 100 μM
Compound: 40
Cytotoxicity against human HepG2 cells incubated for 8 days by cellTiter-Glo assay
Cytotoxicity against human HepG2 cells incubated for 8 days by cellTiter-Glo assay
[PMID: 32816483]
Huh-7 CC50
> 100 μM
Compound: 40
Cytotoxicity against human HuH7 cells incubated for 8 days by cellTiter-Glo assay
Cytotoxicity against human HuH7 cells incubated for 8 days by cellTiter-Glo assay
[PMID: 32816483]
Huh-7 CC50
> 100 μM
Compound: 40
Cytotoxicity against human HuH7 cells infected with HCV con1 subgenomic replicon assessed as reduction in cell viability measured after 3 days by CellTiter-blue cell viability assay
Cytotoxicity against human HuH7 cells infected with HCV con1 subgenomic replicon assessed as reduction in cell viability measured after 3 days by CellTiter-blue cell viability assay
[PMID: 32816483]
Huh-7 EC50
0.014 μM
Compound: 40
Antiviral activity against HCV con1 subgenomic replicon infected in human HuH7 cells assessed as reduction in viral RNA level by qRT-PCR analysis
Antiviral activity against HCV con1 subgenomic replicon infected in human HuH7 cells assessed as reduction in viral RNA level by qRT-PCR analysis
[PMID: 32816483]
MT4 CC50
92 μM
Compound: 40
Cytotoxicity against human MT4 cells incubated for 8 days by cellTiter-Glo assay
Cytotoxicity against human MT4 cells incubated for 8 days by cellTiter-Glo assay
[PMID: 32816483]
U-937 CC50
10 μM
Compound: 40
Cytotoxicity against human U937 cells incubated for 8 days by cellTiter-Glo assay
Cytotoxicity against human U937 cells incubated for 8 days by cellTiter-Glo assay
[PMID: 32816483]
分子量

614.54

Formula

C25H33F2N6O8P
CAS 号
性状

固体

颜色

White to off-white

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
溶解性数据
细胞实验： 

DMSO 中的溶解度 : 125 mg/mL (203.40 mM; 超声助溶; 吸湿的 DMSO 对产品的溶解度有显著影响，请使用新开封的 DMSO)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 1.6272 mL 8.1362 mL 16.2723 mL
5 mM 0.3254 mL 1.6272 mL 3.2545 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只
由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料
参考文献

AL-611 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.6272 mL 8.1362 mL 16.2723 mL 40.6808 mL
5 mM 0.3254 mL 1.6272 mL 3.2545 mL 8.1362 mL
10 mM 0.1627 mL 0.8136 mL 1.6272 mL 4.0681 mL
15 mM 0.1085 mL 0.5424 mL 1.0848 mL 2.7121 mL
20 mM 0.0814 mL 0.4068 mL 0.8136 mL 2.0340 mL
25 mM 0.0651 mL 0.3254 mL 0.6509 mL 1.6272 mL
30 mM 0.0542 mL 0.2712 mL 0.5424 mL 1.3560 mL
40 mM 0.0407 mL 0.2034 mL 0.4068 mL 1.0170 mL
50 mM 0.0325 mL 0.1627 mL 0.3254 mL 0.8136 mL
60 mM 0.0271 mL 0.1356 mL 0.2712 mL 0.6780 mL
80 mM 0.0203 mL 0.1017 mL 0.2034 mL 0.5085 mL
100 mM 0.0163 mL 0.0814 mL 0.1627 mL 0.4068 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AL-6112481279-61-0AL611AL 611HCV ProteaseInhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
AL-611
目录号：
HY-145374
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.