2. Anti-infection
  3. Antibiotic Bacterial Fungal
  4. Alamethicin F 50

Alamethicin F 50 是一种抗生素。Alamethicin F 50 由膜活性肽组成，含有 75% Alamethicin F 50/5 和 10% Alamethicin F 50/7。Alamethicin F 50 通过破坏微生物细胞膜的完整性，导致细胞内容物泄漏和微生物死亡，从而表现出抗真菌和抗菌活性。Alamethicin F 50 能够降低水的表面张力，可用作表面活性剂或洗涤剂。

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Alamethicin F 50 Chemical Structure

Alamethicin F 50 Chemical Structure

CAS No. : 56165-93-6

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规格 是否有货
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Alamethicin F 50 相关抗体

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Aminoglycoside Glycopeptide Lipopeptide Macrolide Oxazolidinone Quinolone Tetracycline β-lactam

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Alamethicin F 50 is an antibiotic. Alamethicin F 50 is composed of membrane-active peptide, containing 75% Alamethicin F 50/5 and 10% Alamethicin F 50/7. Alamethicin F 50 is exhibits antifungal and antibacterial activity by disrupting the integrity of microbial cell membranes, resulting in leakage of cell contents and death of the microorganisms. Alamethicin F 50 is able to reduce the surface tension of water, which can be used as a surfactant or detergent[1][2].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
MDA-MB-231 IC50
5.6 μM
Compound: 1
Cytotoxicity against human MDA-MB-231 cells assessed as decrease in cell viability after 72 hrs by CellTiter 96 AQueous one solution cell proliferation assay
Cytotoxicity against human MDA-MB-231 cells assessed as decrease in cell viability after 72 hrs by CellTiter 96 AQueous one solution cell proliferation assay
[PMID: 28594169]
MDA-MB-435 IC50
4.9 μM
Compound: 1
Cytotoxicity against human MDA-MB-435 cells assessed as decrease in cell viability after 72 hrs by CellTiter 96 AQueous one solution cell proliferation assay
Cytotoxicity against human MDA-MB-435 cells assessed as decrease in cell viability after 72 hrs by CellTiter 96 AQueous one solution cell proliferation assay
[PMID: 28594169]
OVCAR-3 IC50
1.5 μM
Compound: 1
Cytotoxicity against human OVCAR3 cells assessed as decrease in cell viability after 72 hrs by CellTiter 96 AQueous one solution cell proliferation assay
Cytotoxicity against human OVCAR3 cells assessed as decrease in cell viability after 72 hrs by CellTiter 96 AQueous one solution cell proliferation assay
[PMID: 28594169]
分子量

1963.32

Formula

C92H151N23O24
CAS 号
Sequence

Ac-{Aib}-Pro-{Aib}-Ala-{Aib}-Ala-Gln-{Aib}-Val-{Aib}-Gly-Leu-{Aib}-Pro-Val-{Aib}-{Aib}-QQ-{L-Phenylalaninol}
Sequence Shortening

Ac-{Aib}-P-{Aib}-A-{Aib}-AQ-{Aib}-V-{Aib}-GL-{Aib}-PV-{Aib}-{Aib}-QQ-{L-Phenylalaninol}
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Alamethicin F 50 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Alamethicin F 5056165-93-6Alamethicin F50Alamethicin F-50AntibioticBacterialFungalTrichoderma viridedetergentsurfactantInhibitorinhibitorinhibit

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