2. GPCR/G Protein
  3. GLP Receptor
  4. Albiglutide fragment

Albiglutide fragment  (Synonyms: GLP-1-Gly8; GLP-1 (7-36) analog)

目录号: HY-108795
产品使用指南

摩尔计算器

Albiglutide fragment (GLP-1 (7-36) analog) 是 Albiglutide 的活性片段 (7-36)，也是胰高血糖素样肽 -1 (GLP-1) 模拟物 (一种长效的 GLP-1 受体激动剂)。Albiglutide 由抗 DPP-4 的 GLP-1 二聚体与人白蛋白的基因融合产生。Albiglutide fragment 可显著降低糖化血红蛋白 (A1C)，用于 2 型糖尿病 (T2D) 的研究。

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Custom Peptide Synthesis

Albiglutide fragment Chemical Structure

Albiglutide fragment Chemical Structure

CAS No. : 224638-84-0

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Albiglutide fragment 的其他形式现货产品:

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Other Forms of Albiglutide fragment:

Albiglutide fragment 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Albiglutide fragment (GLP-1 (7-36) analog) is an active fragment of Albiglutide (7-36) and a glucagon-like peptide-1 (GLP-1) analog (a long-acting GLP-1 receptor agonist). Albiglutide is produced by the fusion of DPP-4 resistant GLP-1 dimer with the human albumin gene. Moreover, Albiglutide fragment significantly reduces glycosylated hemoglobin (A1C) and is used in type 2 diabetes (T2D) studies[1][2][3][4].

分子量

3283.60

Formula

C148H224N40O45
CAS 号
Sequence

His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-NH2
Sequence Shortening

HGEGTFTSDVSSYLEGQAAKEFIAWLVKGR-NH2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Albiglutide fragment 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Albiglutide fragment224638-84-0GLP-1-Gly8GLP-1 (7-36)GLP Receptortype 2 diabetesmellituslong actinganalogsglucoseT2Dglucagon-like peptide-1 receptorglycosylated hemoglobinA1CInhibitorinhibitorinhibit

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