1. Metabolic Enzyme/Protease
  2. PCSK9
  3. Alirocumab (anti-PCSK9)

Alirocumab (anti-PCSK9)  (Synonyms: 阿利西尤单抗 (anti-PCSK9); REGN 727(anti-PCSK9); SAR 236553(anti-PCSK9))

目录号: HY-P9928A 纯度: 98.24%
COA

Alirocumab (anti-PCSK9) 是一种 PCSK9 的人单克隆抗体。Alirocumab 特异性结合 PCSK9,PCSK9 是肝脏低密度脂蛋白 (LDL) 受体的下调剂,从而提高肝脏结合 LDL-胆固醇 (LDL-C) 的能力并降低血液中的 LDL-C 水平。Alirocumab 可用于高胆固醇血症的研究。

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Alirocumab (anti-PCSK9) Chemical Structure

Alirocumab (anti-PCSK9) Chemical Structure

CAS No. : 1245916-14-6

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MCE 顾客使用本产品发表的 1 篇科研文献

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Alirocumab (anti-PCSK9) is a human monoclonal antibody inhibiting proprotein convertase subtilisin/kexin type 9 (PCSK9). Alirocumab specifically binds PCSK9, a down regulator of liver low-density lipoprotein (LDL)-receptors, thereby increasing the ability of the liver to bind LDL-cholesterol (LDL-C) and reducing levels of LDL-C in blood. Alirocumab can be used for the research of hypercholesterolemia[1][2].

同型

Human IgG1 kappa

推荐同型对照抗体
种属

Human

Clinical Trial
CAS 号
性状

液体

颜色

Colorless to light yellow

中文名称

阿利西尤单抗 (anti-PCSK9)

运输条件

Shipping with dry ice.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Alirocumab (anti-PCSK9)
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HY-P9928A
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