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ALKBH5-IN-2 (compound 6) 是一种有效的 ALKBH5 抑制剂,IC50 值为 0.79 µM。ALKBH5-IN-2 可抑制细胞活力。

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ALKBH5-IN-2 Chemical Structure

ALKBH5-IN-2 Chemical Structure

CAS No. : 1008951-10-7

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

ALKBH5-IN-2 (compound 6) is a potent ALKBH5 inhibitor with an IC50 value of 0.79 µM. ALKBH5-IN-2 inhibits cell viability[1].

体外研究
(In Vitro)

ALKBH5-IN-2 (compound 6) (0-50µM; 48 h) 抑制细胞活力,对 HEK-293T、CCRF-CEM、HL-60、Jurkat、K562、A-172 细胞的 IC50 值分别为 40.5、7.62、11.0、41.3、1.41、>50 µM[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[1]

Cell Line: HEK-293T, CCRF-CEM, HL-60, Jurkat, K562, A-172 cells
Concentration: 0-50 µM
Incubation Time: 48 h
Result: Inhibited cell growth with IC50s of 40.5, 7.62, 11.0, 41.3, 1.41, >50 µM for HEK-293T, CCRF-CEM, HL-60, Jurkat, K562, A-172 cells, respectively.
分子量

209.20

Formula

C9H11N3O3

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • 稀释计算器

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
ALKBH5-IN-2
目录号:
HY-148933
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