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  4. ALKBH5-IN-2

ALKBH5-IN-2 (compound 6) 是一种有效的 ALKBH5 抑制剂，IC50 值为 0.79 µM。ALKBH5-IN-2 可抑制细胞活力。

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ALKBH5-IN-2 Chemical Structure

ALKBH5-IN-2 Chemical Structure

CAS No. : 1008951-10-7

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规格 价格 是否有货 数量
5 mg ￥1500
3 - 5 周
10 mg ￥2500
3 - 5 周
25 mg ￥5250
3 - 5 周
50 mg 现货 3 - 5 周
100 mg 现货 3 - 5 周
200 mg   询价  
500 mg   询价  

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ALKBH5-IN-2 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

ALKBH5-IN-2 (compound 6) is a potent ALKBH5 inhibitor with an IC50 value of 0.79 µM. ALKBH5-IN-2 inhibits cell viability[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
CCRF-CEM IC50
1.38 μM
Compound: 121
Cytotoxicity against human CCRF-CEM cells assessed as reduction in cell viability incubated for 48 hrs
Cytotoxicity against human CCRF-CEM cells assessed as reduction in cell viability incubated for 48 hrs
[PMID: 34792334]
HL-60 IC50
1.38 μM
Compound: 121
Cytotoxicity against human HL-60 cells assessed as reduction in cell viability incubated for 48 hrs
Cytotoxicity against human HL-60 cells assessed as reduction in cell viability incubated for 48 hrs
[PMID: 34792334]
K562 IC50
1.38 μM
Compound: 121
Cytotoxicity against human K562 cells assessed as reduction in cell viability incubated for 48 hrs
Cytotoxicity against human K562 cells assessed as reduction in cell viability incubated for 48 hrs
[PMID: 34792334]
体外研究
(In Vitro)

ALKBH5-IN-2 (compound 6) (0-50µM; 48 h) 抑制细胞活力，对 HEK-293T、CCRF-CEM、HL-60、Jurkat、K562、A-172 细胞的 IC50 值分别为 40.5、7.62、11.0、41.3、1.41、>50 µM[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

ALKBH5-IN-2 相关抗体:

Cell Viability Assay[1]

Cell Line: HEK-293T, CCRF-CEM, HL-60, Jurkat, K562, A-172 cells
Concentration: 0-50 µM
Incubation Time: 48 h
Result: Inhibited cell growth with IC50s of 40.5, 7.62, 11.0, 41.3, 1.41, >50 µM for HEK-293T, CCRF-CEM, HL-60, Jurkat, K562, A-172 cells, respectively.
分子量

209.20

Formula

C9H11N3O3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

ALKBH5-IN-2 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ALKBH5-IN-21008951-10-7OthersHEK-293TCCRF-CEMHL-60JurkatK562 cellscancercell viabilityInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-148933
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