1. Metabolic Enzyme/Protease
  2. Aldose Reductase
  3. ALR2-IN-2

ALR2-IN-2 是一种有效的醛糖还原酶 (ALR2) 抑制剂,抑制大鼠 ALR2ALR1IC50 值分别为为 27 nM 和 228 nM。ALR2-IN-2 可用于研究糖尿病并发症。

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ALR2-IN-2 Chemical Structure

ALR2-IN-2 Chemical Structure

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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

ALR2-IN-2 is a potent inhibitor of aldose reductase (ALR2), with IC50s of 27 nM and 228 nM for rat ALR2 and ALR1, respectively. ALR2-IN-2 can be used for the research of diabetic complications[1].

IC50 & Target

IC50: 27 nM (rat ALR2), 228 nM (rat ALR1)[1]

体外研究
(In Vitro)

ALR2-IN-2 (化合物 2d) 抑制大鼠晶状体 ALR2 和大鼠肾脏 ALR1,IC50 值分别为为 27 nM 和 228 nM[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

358.41

Formula

C17H11FN2O2S2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
ALR2-IN-2
目录号:
HY-151946
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