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Altemicidin  (Synonyms: (-)-Altemicidin)

目录号: HY-N10653
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摩尔计算器

Altemicidin 是一种单萜生物碱，最初从 S. sioyaensis 中分离出来，具有杀螨和抗癌活性。在温室盆栽试验中，浓度为 10 和 100 ppm 时，该物质对二斑蜘蛛螨 (T. urticae) 具有杀螨作用。Altemicidin 可抑制小鼠 L1210 淋巴细胞白血病和 IMC 癌细胞的生长（IC50s 分别为 0.84 和 0.82 μg/mL）。该物质对小鼠有毒性，LD50 值为 0.3 mg/kg。

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Altemicidin Chemical Structure

Altemicidin Chemical Structure

CAS No. : 125399-82-8

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Altemicidin 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Altemicidin is a monoterpene alkaloid originally isolated from S. sioyaensis with acaricidal and anticancer activities. It is acaricidal to two-spotted spider mites (T. urticae) in a greenhouse pot test at concentrations of 10 and 100 ppm. Altemicidin inhibits the growth of murine L1210 lymphocytic leukemia and IMC carcinoma cells (IC50s=0.84 and 0.82 μg/mL, respectively). It is toxic to mice with an LD50 value of 0.3 mg/kg.

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
L1210 IC50
0.84 μM
Compound: 9
Antiproliferative activity against mouse L1210 cells assessed as inhibition of cell proliferation incubated for 48 hrs by Coulter counter method
Antiproliferative activity against mouse L1210 cells assessed as inhibition of cell proliferation incubated for 48 hrs by Coulter counter method
[PMID: 33160760]
L1210 IC50
2.12 μM
Compound: 1
Cytotoxicity against mouse L1210 cells assessed as growth inhibition after 48 hrs by coulter counter analysis
Cytotoxicity against mouse L1210 cells assessed as growth inhibition after 48 hrs by coulter counter analysis
[PMID: 26035239]
分子量

376.39

Formula

C13H20N4O7S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Altemicidin 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

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Keywords:

Altemicidin125399-82-8(-)-AltemicidinOthersInhibitorinhibitorinhibit

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