1. Anti-infection TGF-beta/Smad Stem Cell/Wnt
  2. Bacterial TGF-beta/Smad
  3. Amicoumacin B

Amicoumacin B 可由放线菌菌株 04-5195T 产生。Amicoumacin B 可增加骨形态发生蛋白 2 (BMP-2) 的表达。Amicoumacin B 对 C. violaceum 具有抑制作用 (MIC = 250 µg/mL)。Amicoumacin B 具有群体感应抑制活性,可降低 C. violaceum 操纵子 vioA、vioB、vioD 和 vioE 的表达,但可增加 vioC 的表达。

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Amicoumacin B Chemical Structure

Amicoumacin B Chemical Structure

CAS No. : 77674-99-8

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  • 生物活性

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生物活性

Amicoumacin B can be produced by actinomycete, strain 04-5195T.. Amicoumacin B increases the expression of bone morphogenetic protein 2 (BMP-2). Amicoumacin B has inhibitory effect against C. violaceum (MIC = 250 µg/mL). Amicoumacin B has quorum sensing inhibitory activity, and reduces the expression of the C. violaceum operons vioA, vioB, vioD, and vioE, but increases the expression of vioC[1][2].

分子量

424.44

Formula

C20H28N2O8

CAS 号
结构分类
初始来源

Nocardia jinanensis sp.

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Amicoumacin B
目录号:
HY-N8261
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