1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. Angiotensinogen (1-14), human TFA

Angiotensinogen (1-14), human TFA 

目录号: HY-P1486A
产品使用指南

Angiotensinogen (1-14), human TFA 是肾素底物血管紧张素原 (angiotensinogen) 的片段,血管紧张素原是天然存在的肾素底物,也是所有血管紧张素肽的前体。

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Custom Peptide Synthesis

Angiotensinogen (1-14), human TFA Chemical Structure

Angiotensinogen (1-14), human TFA Chemical Structure

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Angiotensinogen (1-14), human TFA 的其他形式现货产品:

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Other Forms of Angiotensinogen (1-14), human TFA:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Angiotensinogen (1-14), human TFA is a fragment of the renin substrate angiotensinogen. Angiotensinogen is naturally occurring substrate for renin and a precursor for all angiotensin peptides[1][2].

IC50 & Target[1][2]

Human Endogenous Metabolite

 

体外研究
(In Vitro)

Angiotensinogen (AGT) is the only precursor of all angiotensin peptides. Human AGT has 485 amino acids, including a 33 amino-acid signal peptide. The 10 N-terminal amino acids are cleaved by renin to provide angiotensin I (AngI), which is the source for an array of active angiotensin peptides[1].
Angiotensinogen isolated from most species is cleaved by human renin. Synthetic peptides containing the N-terminal amino-acid sequence of angiotensinogen were renin substrates[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

1760.01 (free acid)

Formula

C83H122N24O19.xC2HF3O2

Sequence Shortening

DRVYIHPFHLVIHN

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Angiotensinogen (1-14), human TFA
目录号:
HY-P1486A
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