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Anisodine hydrobromide  (Synonyms: 氢溴酸樟柳碱)

目录号: HY-127022A
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Anisodine hydrobromide 是一种神经保护化合物,可与脑缺血性疾病中的毒蕈碱受体(M1-M5)相互作用。Anisodine hydrobromide 可有效降低缺氧/复氧条件下脑组织中加剧的 M1、M2、M4 和 M5 受体表达。Anisodine hydrobromide 表现出浓度依赖性的钙离子内流和活性氧 (ROS) 水平抑制,阐明了其神经保护机制。Anisodine hydrobromide 导致缺氧期间 HM 细胞中的天冬氨酸水平降低,突出了其对神经递质调节的影响。Anisodine hydrobromide 作为缺血性脑病的潜在抑制剂具有良好的临床前景,值得进一步研究其作用机制。

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Anisodine hydrobromide Chemical Structure

Anisodine hydrobromide Chemical Structure

CAS No. : 76822-34-9

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生物活性

Anisodine hydrobromide is a neuroprotective compound that interacts with muscarinic receptors (M1-M5) in cerebral ischemic diseases. Anisodine hydrobromide effectively reduces exacerbated M1, M2, M4, and M5 receptor expression in brain tissues under hypoxia/reoxygenation conditions. Anisodine hydrobromide demonstrates concentration-dependent inhibition of calcium ion influx and reactive oxygen species (ROS) levels, elucidating its neuroprotective mechanisms. Anisodine hydrobromide leads to decreased aspartate levels in HM cells during hypoxia, highlighting its effects on neurotransmitter modulation. Anisodine hydrobromide holds promising clinical prospects as a potential therapeutic agent for ischemic brain diseases, warranting further investigation into its mechanisms of action.

分子量

400.26

Formula

C17H22BrNO5

CAS 号
中文名称

氢溴酸樟柳碱

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Anisodine hydrobromide 相关分类

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Anisodine hydrobromide
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HY-127022A
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