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  3. ANK peptide

ANK peptide 是一种基于单锚蛋白基序保守残基设计的新型肽。ANK peptide 是 γ-突触核蛋白 (SNCG) 的抑制剂,可与 SNCG 结合,竞争 SNCG-BubR1 相互作用,从而增强乳腺癌细胞对抗微管药物 (如诺考达唑和紫杉醇) 的敏感性。ANK peptide 可用于肿瘤的研究。

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Custom Peptide Synthesis

ANK peptide Chemical Structure

ANK peptide Chemical Structure

CAS No. : 929207-58-9

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  • 生物活性

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生物活性

ANK peptide is a novel peptide designed based on the conserved residues of single ankyrin motif. ANK peptide is a synuclein-γ (SNCG) inhibitor that binds to SNCG and competes with SNCG-BubR1 interaction to enhance the sensitivity of breast cancer cells to antimicrotubule drugs such as nocodazole and paclitaxel. ANK peptide can be used in the study of cancer[1].

分子量

3600.01

Formula

C152H244N52O46S2

CAS 号
Sequence

Lys-Gly-Asn-Ser-Ala-Leu-His-Val-Ala-Ser-Gln-His-Gly-His-Leu-Gly-Cys-Ile-Gln-Thr-Leu-Val-Arg-Tyr-Gly-Ala-Asn-Val-Thr-Met-Gln-Asn-His-Gly

Sequence Shortening

KGNSALHVASQHGHLGCIQTLVRYGANVTMQNHG

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
ANK peptide
目录号:
HY-P10844
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