1. Metabolic Enzyme/Protease Anti-infection
  2. Glutathione S-transferase Parasite
  3. Anonaine

Anonaine 是一种抗寄生虫剂。Anonaine 也是一种谷胱甘肽 S-转移酶 (glutathione S-transferase (GST)) 抑制剂。

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Anonaine Chemical Structure

Anonaine Chemical Structure

CAS No. : 1862-41-5

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规格 价格 是否有货 数量
1 mg ¥3366
In-stock
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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Anonaine is an antiparasitic agent. Anonaine also is a glutathione S-transferase (GST) inhibitor[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
A-431 ED50
4.2 μg/mL
Compound: 3
Cytotoxicity against human A431 cells after 3 days by SRB assay
Cytotoxicity against human A431 cells after 3 days by SRB assay
[PMID: 8254346]
AGS IC50
8.6 μM
Compound: 5
Cytotoxicity against human AGS cells by MTS colorimetric assay
Cytotoxicity against human AGS cells by MTS colorimetric assay
[PMID: 11087586]
DLD-1 IC50
28.9 μM
Compound: 5
Cytotoxicity against human DLD1 cells by MTS colorimetric assay
Cytotoxicity against human DLD1 cells by MTS colorimetric assay
[PMID: 11087586]
HeLa IC50
24.8 μg/mL
Compound: Anonaine, III
Cytotoxicity against human HeLa cells after 24 hrs by MTT assay
Cytotoxicity against human HeLa cells after 24 hrs by MTT assay
[PMID: 18295494]
Hepatocyte IC50
70.3 μg/mL
Compound: Anonaine, III
Cytotoxicity against Sprague-Dawley rat primary hepatocytes after 24 hrs by MTT assay
Cytotoxicity against Sprague-Dawley rat primary hepatocytes after 24 hrs by MTT assay
[PMID: 18295494]
HepG2 IC50
20.8 μM
Compound: 5
Cytotoxicity against human HepG2 cells by MTS colorimetric assay
Cytotoxicity against human HepG2 cells by MTS colorimetric assay
[PMID: 11087586]
HepG2 IC50
33.5 μg/mL
Compound: Anonaine, III
Cytotoxicity against human HepG2 cells after 24 hrs by MTT assay
Cytotoxicity against human HepG2 cells after 24 hrs by MTT assay
[PMID: 18295494]
HT-1080 ED50
2.4 μg/mL
Compound: 3
Cytotoxicity against human HT1080 cells after 3 days by SRB assay
Cytotoxicity against human HT1080 cells after 3 days by SRB assay
[PMID: 8254346]
KB ED50
2.6 μg/mL
Compound: 3
Cytotoxicity against human KB cells after 3 days by SRB assay
Cytotoxicity against human KB cells after 3 days by SRB assay
[PMID: 8254346]
KB-V1 ED50
1.8 μg/mL
Compound: 3
Cytotoxicity against vinblastine-resistant human KBV1 cells after 3 days by SRB assay
Cytotoxicity against vinblastine-resistant human KBV1 cells after 3 days by SRB assay
[PMID: 8254346]
LNCaP ED50
2.9 μg/mL
Compound: 3
Cytotoxicity against human LNCAP cells after 3 days by SRB assay
Cytotoxicity against human LNCAP cells after 3 days by SRB assay
[PMID: 8254346]
P388 ED50
> 5 μg/mL
Compound: 3
Cytotoxicity against mouse P388 cells after 3 days by SRB assay
Cytotoxicity against mouse P388 cells after 3 days by SRB assay
[PMID: 8254346]
SK-MEL-2 ED50
15.8 μg/mL
Compound: 3
Cytotoxicity against human SK-MEL-2 cells after 3 days by SRB assay
Cytotoxicity against human SK-MEL-2 cells after 3 days by SRB assay
[PMID: 8254346]
U-373MG ATCC ED50
1.5 μg/mL
Compound: 3
Cytotoxicity against human U373 cells after 3 days by SRB assay
Cytotoxicity against human U373 cells after 3 days by SRB assay
[PMID: 8254346]
ZR-75-1 ED50
2.7 μg/mL
Compound: 3
Cytotoxicity against human ZR-75-1 cells after 3 days by SRB assay
Cytotoxicity against human ZR-75-1 cells after 3 days by SRB assay
[PMID: 8254346]
分子量

265.31

Formula

C17H15NO2

CAS 号
性状

固体

颜色

Light brown to brown

结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

产品名称:
Anonaine
目录号:
HY-N7227
需求量: