1. Anti-infection
  2. Bacterial
  3. Anoplin

Anoplin 是一种存在于独居胡蜂 (Anoplius samariensis) 毒液中的抗微生物肽。Anoplin 对包括革兰氏阳性和阴性细菌在内的多种细菌都表现出了抗菌活性。Anoplin 可用于抗生素的开发。

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Custom Peptide Synthesis

Anoplin Chemical Structure

Anoplin Chemical Structure

CAS No. : 321352-67-4

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Anoplin is an antimicrobial peptide found in the venom of the solitary wasp (Anoplius samariensis). Anoplin exhibits antimicrobial activity against a wide range of bacteria, including both gram-positive and gram-negative bacteria. Anoplin can be used in the development of antibiotics[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
4T1 IC50
191.03 μM
Compound: Anoplin
Antiproliferative activity against triple-negative mouse 4T1 cells assessed as inhibition of cell growth measured after 24 hrs by Cell Counting Kit-8 assay
Antiproliferative activity against triple-negative mouse 4T1 cells assessed as inhibition of cell growth measured after 24 hrs by Cell Counting Kit-8 assay
[PMID: 33844923]
B16-F10 IC50
> 400 μM
Compound: Anoplin
Antiproliferative activity against mouse B16-F10 cells assessed as inhibition of cell growth measured after 24 hrs by Cell Counting Kit-8 assay
Antiproliferative activity against mouse B16-F10 cells assessed as inhibition of cell growth measured after 24 hrs by Cell Counting Kit-8 assay
[PMID: 33844923]
Erythrocyte EC50
> 500 μg/mL
Compound: 10
Hemolytic activity in sheep erythrocytes after 1 hr
Hemolytic activity in sheep erythrocytes after 1 hr
[PMID: 23719232]
分子量

1153.50

Formula

C54H104N16O11

CAS 号
Sequence

Gly-Leu-Leu-Lys-Arg-Ile-Lys-Thr-Leu-Leu-NH2

Sequence Shortening

GLLKRIKTLL-NH2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Anoplin
目录号:
HY-P10518
需求量: