2. Anti-infection
  3. Bacterial
  4. Anti-MRSA agent 10

Anti-MRSA agent 10 (Compound 2d) 是一种头孢菌素 Cephalosporin (HY-144229) 衍生物，具有抗菌活性。Anti-MRSA agent 10 具有轻微的耐药性，并且在 HUVEC 和 HBZY-1 细胞中表现出较低的细胞毒性。

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Anti-MRSA agent 10 Chemical Structure

Anti-MRSA agent 10 Chemical Structure

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Anti-MRSA agent 10 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Anti-MRSA agent 10 (Compound 2d) is a Cephalosporin (HY-144229) derivative and exhibits antibacterial activity. Anti-MRSA agent 10 is slightly drug resistane and exhibits low cytotoxicity in cells HUVEC and HBZY-1[1].

体外研究
(In Vitro)

Anti-MRSA agent 10 对绵羊红细胞，HUVECs 和 HBZY-1 cells 无明显细胞毒性，安全剂量大于 128 μg/mL[1]。
Anti-MRSA agent 10 对革兰氏阴性 Stenotrophomonas maltophilia 和 Staphylococcus aureus，革兰氏阳性 Escherichia coli 和 Stenotrophomonas maltophilia，以及抗药性 Staphylococcus aureus (MRSA) 具有抗菌活性，MIC 分别为 0.7，4，8，8 和 2-4 μg/mL[1]。
Anti-MRSA agent 10 (0-128 μg/mL) 通过靶向青霉素结合蛋白 (PBP)，破坏细菌细胞壁结构并促进氧化损伤抑制细菌 S. aureus 的细胞呼吸和活力[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Anti-MRSA agent 10 相关抗体:

Cell Viability Assay[1]

Cell Line: S. Aureus, HUEVC, HBZY-1
Concentration: 0-128 μg/mL
Incubation Time: 48 h
Result: Inhibited metabolic process of S. aureus.
Maintained viability of HUVEC and HBZY-1 cells.
分子量

743.77

Formula

C30H36F3N7O8S2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Anti-MRSA agent 10 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anti-MRSA agent 10BacterialStenotrophomonas maltophiliaStaphylococcus aureusEscherichia colicephalosporinInhibitorinhibitorinhibit

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目录号：
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