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  5. Anti-osteoporosis agent-2

Anti-osteoporosis agent-2 (Compound 10) 是一种抗骨质疏松剂。Anti-osteoporosis agent-2 抑制 RANKL 诱导的破骨细胞分化。

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Anti-osteoporosis agent-2 Chemical Structure

Anti-osteoporosis agent-2 Chemical Structure

CAS No. : 849693-09-0

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规格 价格 是否有货 数量
1 mg ¥3100
1 - 2 周
5 mg 现货 1 - 2 周
10 mg   询价  
50 mg   询价  

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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Anti-osteoporosis agent-2 (Compound 10) is an anti-osteoporosis agent. Anti-osteoporosis agent-2 inhibits differentiation on osteoclast induced by RANKL[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
RAW264.7 IC50
2.3 μM
Compound: 15
Inhibition of LPS-induced NO production in mouse RAW264.7 cells preincubated for 2 hrs followed by LPS stimulation for 24 hrs by Griess reagent based assay
Inhibition of LPS-induced NO production in mouse RAW264.7 cells preincubated for 2 hrs followed by LPS stimulation for 24 hrs by Griess reagent based assay
[PMID: 34726063]
体外研究
(In Vitro)

Anti-osteoporosis agent-2 (Compound 10; 0.03-10 μM; 4-5 days) 抑制 RANKL 诱导的 BMM 成骨细胞分化,IC50 为 0.83 μM[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

364.43

Formula

C20H28O6

CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Anti-osteoporosis agent-2
目录号:
HY-N11514
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