1. Anti-infection
  2. Bacterial
  3. Antibacterial agent 12

Antibacterial agent 12 是一种联芳基恶唑烷酮类似物,是一种针对抗生素敏感和耐药革兰氏阳性菌的抗菌剂。

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Antibacterial agent 12 Chemical Structure

Antibacterial agent 12 Chemical Structure

CAS No. : 2382921-99-3

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Antibacterial agent 12, a biaryloxazolidinone analogue, is an antibacterial agent against antibiotic-susceptible and antibiotic-resistant Gram-positive bacteria[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
HepG2 IC50
> 25 μM
Compound: 14a-7
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
[PMID: 31654879]
体外研究
(In Vitro)

Antibacterial agent 12 (compound 14a-7) exhibits a MIC value of 0.125 μg/mL against S.aureus[1].
Antibacterial agent 12 (compound 14a-7) is stable in human liver microsome. Antibacterial agent 12 exhibits lower inhibitory activity against human MAO-A compared to Linezolid[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

489.52

Formula

C22H24FN5O5S

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Antibacterial agent 12 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Antibacterial agent 12
目录号:
HY-126629
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