BMP2 抗体

BMP2 Antibody is an unconjugated, approximately 13/44 kDa, rabbit-derived, anti-BMP2 polyclonal antibody. BMP2 Antibody can be used for: WB, ELISA, IHC-P, IHC-F, IF expriments in human, mouse, rat, and predicted: chicken, dog, cow, horse, rabbit, sheep background without labeling.

神经干细胞标志物 BMP-2主要对未分化间充质细胞和骨系细胞起到募集和分化作用。在骨形成早期，BMP-2不仅可使未分化间质细胞向骨形成中心募集，并分化为骨系细胞，而且可使成纤维细胞、成肌细胞及骨髓的基细胞逆转分化为骨系细胞。其主要过程是：增加或抑制这些细胞内的某些特异性蛋白的分泌，使成纤维细胞分化为成骨细胞，成肌细胞快速分化为肥大的软骨细胞，并促进基质钙化。 对于成骨细胞，BMP-2则可使之维持其特有细胞表型，并诱导成骨细胞标志物的增高，促进细胞外基质钙化。在骨形成后期，BMP-2还作为一种破骨细胞分化因子与其它支持破骨细胞分化因子直接或间接刺激破骨细胞分化，参与骨的重建。

650

Predicted band size: 13/44kDa

affinity purified

Secreted.

Non-conjugated

Unmodified

Primary Antibody; Rabbit Polyclonal Antibody

Polyclonal

Rabbit

Human, Mouse, Rat

Chicken, Dog, Cow, Horse, Rabbit, Sheep

P12643

WB: 1:500-2000;ELISA: 1:5000-10000;IHC-P: 1:100-500;IHC-F: 1:100-500;IF: 1:100-500

• 
  Western blot analysis of extracts from M-Spleen using BMP2 antibody. Proteins were transferred to a PVDF membrane and blocked with 5% nonfat powdered milk in PBST for 2 hour at room temperature. The primary antibody (1/2000) and Loading control antibody (GAPDH, 1/3000) was diluted with 5% nonfat powdered milk in PBST at 4°C overnight. Goat Anti-Rabbit IgG-HRP Secondary Antibody (1/8,000) was incubated for 45min at room temperature.

WB, ELISA, IHC-P, IHC-F, ICC/IF

液体

Supplied in 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

KLH conjugated synthetic peptide derived from human BMP2: 283-365/396