PP1C alpha/beta 抗体 (YA1700)

PP1C alpha/beta Antibody (YA1700) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1700), targeting PP1C alpha/beta, with a predicted molecular weight of 38 kDa (observed band size: 38 kDa). PP1C alpha/beta Antibody (YA1700) can be used for WB, IHC-P, IP experiment in human, mouse, rat background.

The protein encoded by The related gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). The broadly expressed related gene encodes the alpha subunit of the PP1 complex that associates with over 200 regulatory proteins to form holoenzymes which dephosphorylate their biological targets with high specificity. PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies suggest that PP1 is an important regulator of cardiac function and that PP1 deregulation is implicated in diabetes and multiple types of cancer. Three alternatively spliced transcript variants encoding different isoforms have been found for The related gene.

5499

Predicted band size: 38 kDa; Observed band size: 38 kDa

Affinity Purified

Non-conjugated

Unmodified

Signal Transduction

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Recombinant, Monoclonal

Rabbit

Human, Mouse, Rat

P62136

WB: 1/500-1/1000;IHC: 1/50-1/100;IP: 1/20

WB, IHC-P, IP

液体

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

A synthetic peptide of human PPP1CA+PPP1CB