Thyroglobulin 抗体 (YA2199)

Thyroglobulin Antibody (YA2199) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2199), targeting Thyroglobulin, with a predicted molecular weight of 305 kDa (observed band size: 305 kDa). Thyroglobulin Antibody (YA2199) can be used for WB, IP experiment in human background.

Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in The related gene cause thyroid dyshormonorelated genesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in The related gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis.

7038

Predicted band size: 305 kDa; Observed band size: 305 kDa

Affinity Chromatography

Non-conjugated

Unmodified

Signal Transduction

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Recombinant, Monoclonal

Rabbit

Human

P01266

WB: 1/500-1/1000;IP: 1/50

WB, IP

液体

Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

A synthesized peptide derived from human Thyroglobulin