1. Apoptosis
  2. Necroptosis
  3. Anticancer agent 146

Anticancer agent 146 (compound 1.19) 是一种坏死 (Necroptosis) 诱导剂。Anticancer agent 146 在小鼠 MDA-MB-231 异种移植模型中具有抗肿瘤功效。

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Anticancer agent 146 Chemical Structure

Anticancer agent 146 Chemical Structure

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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Anticancer agent 146 (compound 1.19) is a necroptosis inducer. Anticancer agent 146 has anti-tumor efficacy in the mouse MDA-MB-231 xenograft model[1].

体外研究
(In Vitro)

Anticancer agent 146 (compound 1.19) 抑制不同癌细胞系的 IC50s 分别为 8.54 μM (MDA-MB-231),4.24 μM (MCF7),4.67 μM (4T1),8.02 μM (67NR),3.36 μM (MIAPaCa-2),和 1.76 μM (WiDr)[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

375.25

Formula

C19H16Cl2N2O2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Anticancer agent 146 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Anticancer agent 146
目录号:
HY-155146
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