1. Membrane Transporter/Ion Channel
  2. P-glycoprotein BCRP
  3. Anticancer agent 191

Anticancer agent 191 (Compound 2) 是一种丙磺舒 (HY-B0545) 衍生物。Anticancer agent 191 是一种针对癌症细胞的排出抑制剂,旨在抑制 P-糖蛋白 (P-gp)、乳腺癌耐药蛋白 (BCRP) 和/或多种多药耐药蛋白 (MRPs)。Anticancer agent 191 增加长春碱在癌症细胞内的积累,用于癌症的研究。

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Anticancer agent 191 Chemical Structure

Anticancer agent 191 Chemical Structure

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Anticancer agent 191 (Compound 2) is a derivative of probenecid (HY-B0545). As a cancer cell efflux inhibitor, Anticancer agent 191 is designed to inhibit P-glycoprotein (P-gp), breast cancer resistance protein (BCRP), and/or multiple multidrug resistance proteins (MRPs). Anticancer agent 191 increases the accumulation of vinblastine in cancer cells, which is used for cancer research[1].

分子量

413.53

Formula

C19H31N3O5S

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Anticancer agent 191
目录号:
HY-157876
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