2. GPCR/G Protein Neuronal Signaling
  3. mAChR
  4. Antidepressant agent 6

Antidepressant agent 6 (S-3a) 是一种具有强效和持久抗抑郁效果的先导化合物。Antidepressant agent 6 (S-3a) 显示出高的认知安全。Antidepressant agent 6 (S-3a) 拮抗M1受体并提高BDNF水平，可用于抗抑郁症研究。

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Antidepressant agent 6 Chemical Structure

Antidepressant agent 6 Chemical Structure

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Antidepressant agent 6 相关抗体

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mAChR1 mAChR2 mAChR3 mAChR4 mAChR5

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Antidepressant agent 6 (S-3a) is a lead compound with potent and sustained antidepressant effects. Antidepressant agent 6 (S-3a) displays high cognitive safety margin.Antidepressant agent 6 (S-3a) antagonizes M1 receptors and elevates BDNF levels, suggesting its potential as an antidepressant for further exploration[1].
体内研究
(In Vivo)

Antidepressant agent 6 (S-3a) 缓解了小鼠的抑郁症状，并且比东莨菪碱显示出更高的认知安全裕度[1].
Antidepressant agent 6 (S-3a)缓解了慢性应激反应 (CRS)小鼠的绝望行为[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Reserpine-Induced Depression Model in Mice[1].
Dosage: 25, 100, or 300 μg/kg.
Administration: Administered intraperitoneally every other day.
Result: Did not cause changes in total distance during the OFT, suggesting its antidepressant-like effects were independent of locomotor activity.
Could alleviate depression-induced weight loss relative to the untreated model group.
分子量

321.34

Formula

C17H20FNO4
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Antidepressant agent 6 相关分类

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antidepressant agent 6Antidepressant agent6Antidepressant agent-6mAChRMuscarinic acetylcholine receptordepressionBNDFCRSM1 receptorInhibitorinhibitorinhibit

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