2. Anti-infection
  3. Fungal
  4. Antifungal agent 51

Antifungal agent 51 (Compound 5c) 具有强效的抗真菌活性，尤其是对白色念珠菌 FDC 151 、近平滑念珠菌 ATCC 22019 和热带假丝酵母 FDC 138，MIC 值小于 0.063 μg/mL，而对细胞的毒性较低，无致癌性。

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Antifungal agent 51 Chemical Structure

Antifungal agent 51 Chemical Structure

CAS No. : 2896209-47-3

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Antifungal agent 51 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Antifungal agent 51 (Compound 5c) has potent antifungal activity, especially against Candida albicans FDC 151 , Candida parapsilosis ATCC 22019 and Candida tropicalis FDC 138, with the MIC value is less than 0.063 μg/mL, and it has low toxicity to cells and no carcinogenicity[1].

体外研究
(In Vitro)

Antifungal agent 51 具有很强的抗真菌活性，尤其是对白色念珠菌 FDC 151、近平滑念珠菌 ATCC 22019 和热带念珠菌 FDC 138，具有 MIC 值 小于 0.063 μg/mL，对白色念珠菌 CMRC 19 和光滑念珠菌FDC 192，MIC 值为 0.125 μg/mL，对白色念珠菌 CMRC 192，MIC 值为 0.25 μg/mL，对抗光滑念珠菌 CMRC 89，MIC 值为 1 μg/mL[1]。
Antifungal agent 51（6.25、12.5、25 μg/mL；48 小时）在 BEAS-2B 和 HepG2 细胞中即使在 25 μg/mL 的相对高浓度下也会部分影响细胞系的活力[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Antifungal agent 51 相关抗体:

Cell Viability Assay[1]

Cell Line: BEAS-2B and HepG2 cells
Concentration: 6.25, 12.5, and 25 μg/mL
Incubation Time: 48 h
Result: Partially affected the viability of cell lines even at relatively high concentration of 25 μg/mL in BEAS-2B and HepG2 cells
分子量

369.42

Formula

C18H16FN5OS
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Antifungal agent 51 相关分类

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antifungal agent 512896209-47-3Antifungal agent51Antifungal agent-51FungalAntifungalCandida albicans FDC 151 Candida parapsilosis ATCC 22019Candida tropicalis FDC 138Inhibitorinhibitorinhibit

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