2. Anti-infection
  3. Parasite
  4. Antiparasitic agent-4

Antiparasitic agent-4 (compound 4q) 对婴儿利什曼原虫 (L. infantum) 和克氏锥虫 (T. cruzi) 具有较高的抗寄生活性，IC50 分别为 8.51 μM 和 2.20 μM。Antiparasitic agent-4 对癌细胞 HepG2 也具有一定的细胞毒性 (CC50 = 18.97 μM)。

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Antiparasitic agent-4 Chemical Structure

Antiparasitic agent-4 Chemical Structure

CAS No. : 2253996-66-4

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Antiparasitic agent-4 相关抗体

Top Publications Citing Use of Products

查看 Parasite 亚型特异性产品:

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Amebae Coccidia Leishmania Mite Plasmodium Toxoplasma Trypanosoma Schistosome

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Antiparasitic agent-4 (compound 4q) has highly antiparasitic activity against Leishmania infantum (L. infantum) and Trypanosoma cruzi (T. cruzi) with IC50s of 8.51 μM and 2.20 μM, respectively. Antiparasitic agent-4 also has certain cytotoxicity against HepG2 (CC50 = 18.97 μM)[1].

IC50 & Target

Trypanosoma

 

Leishmania

 

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
HepG2 CC50
18.97 μM
Compound: 4q
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 120 hrs by MTS assay
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 120 hrs by MTS assay
[PMID: 32590115]
HFF-1 CC50
> 64 μM
Compound: 4q
Cytotoxicity against human HFF-1 cells assessed as reduction in cell viability incubated for 120 hrs by MTS assay
Cytotoxicity against human HFF-1 cells assessed as reduction in cell viability incubated for 120 hrs by MTS assay
[PMID: 32590115]
分子量

279.29

Formula

C16H13N3O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Antiparasitic agent-4 相关分类

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  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antiparasitic agent-42253996-66-4Antiparasitic agent4Antiparasitic agent 4ParasiteL. InfantumT. cruziAntiparasiticIntracellular amastigotesHepG2Inhibitorinhibitorinhibit

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