2. Apoptosis
  3. Caspase Apoptosis
  4. Antiproliferative agent-42

Antiproliferative agent-42 (compound 7m) 是一种二氢双吡咯化合物。Antiproliferative agent-42 对 Panc-1 细胞系具有抗增殖活性，IC50 为 12.54 μM。

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Antiproliferative agent-42 Chemical Structure

Antiproliferative agent-42 Chemical Structure

CAS No. : 3002404-74-9

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Antiproliferative agent-42 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Antiproliferative agent-42 (compound 7m) is a dihydrodipyrrolo compound. Antiproliferative agent-42 showed antiproliferative activity against Panc-1 cell line with an IC50 value of 12.54 μM[1].

体外研究
(In Vitro)

Antiproliferative agent-42 (0-100 μM, 48 h) 对 Panc-1、 PC3、 MDA-MB-231 细胞有抑制作用，IC50 分别是 12.5 μM、17.7 μM、and 13.1 μM[1]。
Antiproliferative agent-42 (12.54 μM, 48 h) 在 Panc-1 细胞中能够诱导 sub-G1 期阻滞[1]。
Antiproliferative agent-42 (12.54 μM) 在 Panc-1 细胞中使得 cleaved-caspase-3 和 caspase-3 蛋白下调，而 pro-caspase-3 蛋白水平保持不变[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Antiproliferative agent-42 相关抗体:

Apoptosis Analysis[1]

Cell Line: Panc-1
Concentration: 12.54 μM
Incubation Time: 48 h
Result: Induced apoptosis at 15.54 μM concentration (11.1%).
分子量

363.33

Formula

C18H13N5O4
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Antiproliferative agent-42 相关分类

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  • Do most proteins show cross-species activity?

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Keywords:

Antiproliferative agent-423002404-74-9Antiproliferative agent42Antiproliferative agent 42CaspaseApoptosiscytotoxic agentantiproliferativePanc-1 cellsInhibitorinhibitorinhibit

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