2. Anti-infection
  3. Parasite
  4. Antitrypanosomal agent 4

Antitrypanosomal agent 4 (compound 19) 是一种有效且具有血脑屏障渗透性的抗锥体虫剂，对克氏锥虫 (T. cruzi) 和布氏锥虫 (T. b. brucei) 有良好的抗性，IC50 分别为 1.2 μM 和 70 nM。

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Antitrypanosomal agent 4 Chemical Structure

Antitrypanosomal agent 4 Chemical Structure

CAS No. : 2456427-48-6

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Antitrypanosomal agent 4 相关抗体

Top Publications Citing Use of Products

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Amebae Coccidia Leishmania Mite Plasmodium Toxoplasma Trypanosoma Schistosome

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Antitrypanosomal agent 4 (compound 19) is a potent and blood-brain barrier permeable antitrypanosomal agent. Antitrypanosomal agent 4 has good activity against Trypanosoma cruzi (T. cruzi) and Trypanosoma brucei brucei (T. b. brucei) with IC50s of 1.2 μM and 70 nM, respectively[1]. Antitrypanosomal agent 4 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC50 & Target

Trypanosoma

 

分子量

419.84

Formula

C18H14ClN3O5S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Antitrypanosomal agent 4 相关分类

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antitrypanosomal agent 42456427-48-6Antitrypanosomal agent4Antitrypanosomal agent-4ParasiteT.CruziT.b.bruceiAntitrypanosomalBBB permeableInhibitorinhibitorinhibit

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