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  4. Antitumor agent-162

Antitumor agent-162 (compound 52a) 是一种有效的，具有口服活性的抗肿瘤剂。Antitumor agent-162 具有细胞毒性。

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Antitumor agent-162 Chemical Structure

Antitumor agent-162 Chemical Structure

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     可免费申领三个不同产品的试用装。

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Customer Review

Antitumor agent-162 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Antitumor agent-162 (compound 52a) is a potent and orally active antitumor agent. Antitumor agent-162 shows cytotoxicity[1].

体外研究
(In Vitro)

Antitumor agent-162 (compound 52a) (0-5000 nM) 表现出细胞毒性，对 Mut6、UTSW63 细胞的 IC50 值分别为 63、84 nM[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Antitumor agent-162 相关抗体:
体内研究
(In Vivo)

药代动力学分析[1]。

route T1/2 (h) Cmax (ng/mL) Tmax (h) AUClast (ng*min/mL) CL kp (AUCbrain/AUCplasma)
plasma i.p. (10 mg/kg) 234 1303 30 289860 0.13 -
i.v. (5 mg/kg) 189 12000 5 885630 0.14 -
p.o. (20 mg/kg) 208 3404 30 1387613 0.14 -
brain i.p. (10 mg/kg) 182 2526 90 720503 - 2.49
i.v. (5 mg/kg) 294 3257 5 767638 - 0.87
p.o. (20 mg/kg) 254 2381 90 1774789 - 1.28

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

480.34

Formula

C26H19Cl2NO4
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Antitumor agent-162 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antitumor agent-162Antitumor agent162Antitumor agent 162Othersorally activeantitumorcytotoxicityMut6UTSW63 cellInhibitorinhibitorinhibit

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产品名称：
Antitumor agent-162
目录号：
HY-162560
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