2. Membrane Transporter/Ion Channel Apoptosis
  3. Apoptosis BCRP
  4. Antitumor photosensitizer-4

Antitumor photosensitizer-4 (compound 10b) 是一种有效的靶向 ABCG2 的酪氨酸激酶抑制剂 (TKI)。Antitumor photosensitizer-4 是一种光敏剂 (PS)，由达沙替尼 (HY-10181) 和伊马替尼 (HY-15463) 的偶联物组成。Antitumor photosensitizer-4 诱导细胞凋亡 (apoptosis) 和 ROS 产生，对 HepG2 和 B16-F10 细胞表现出强光毒性。

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Antitumor photosensitizer-4 Chemical Structure

Antitumor photosensitizer-4 Chemical Structure

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Antitumor photosensitizer-4 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Antitumor photosensitizer-4 (compound 10b) is a potent tyrosine kinase inhibitor (TKI) targeting ABCG2. Antitumor photosensitizer-4 is a photosensitizer (PS) consisting of a conjugate of dasatinib (HY-10181) and imatinib (HY-15463). Antitumor photosensitizer-4 induces apoptosis and ROS production and exhibits strong phototoxicity to HepG2 and B16-F10 cells[1].

体外研究
(In Vitro)

Antitumor photosensitizer-4

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Antitumor photosensitizer-4 相关抗体:
体内研究
(In Vivo)

Antitumor photosensitizer-4

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

1269.90

Formula

C65H77ClN12O11S
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Antitumor photosensitizer-4 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antitumor photosensitizer-4Antitumor photosensitizer4Antitumor photosensitizer 4ApoptosisBCRPBreast cancer resistance proteinABCG2Chlorin e(6)Photodynamic therapy (PDT)PhotosensitizerTyrosine kinase inhibitorsInhibitorinhibitorinhibit

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