2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. GABA Receptor
  4. Anxiolytic/nonsedative agent-1

Anxiolytic/nonsedative agent-1 

目录号: HY-103521
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摩尔计算器

Anxiolytic/nonsedative agent-1 (compound 2b) 是一种有效的选择性 GABAA 激动剂。Anxiolytic/nonsedative agent-1 对牛脑膜中的 BzR 显示出明显的亲和力，对 α1β2γ2、α2β2γ2、α5β3γ2 的 Kis 分别为 14、121、239 nM。Anxiolytic/nonsedative agent-1 在体外表现出 α2 选择性功效，在体内表现出抗焦虑选择性作用。

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Anxiolytic/nonsedative agent-1 Chemical Structure

Anxiolytic/nonsedative agent-1 Chemical Structure

CAS No. : 355022-97-8

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规格 价格 是否有货 数量
1 mg ￥2084
1 - 2 周
5 mg   询价  
10 mg   询价  

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Anxiolytic/nonsedative agent-1 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Anxiolytic/nonsedative agent-1 (compound 2b) is a potent and selective GABAA agonist. Anxiolytic/nonsedative agent-1 shows appreciable affinity for the BzR in bovine brain membranes with Kis of 14, 121, 239 nM for α1β2γ2, α2β2γ2, α5β3γ2, respectively. Anxiolytic/nonsedative agent-1 shows α2 selective efficacy in vitro and anxioselective effects in vivo[1].

分子量

337.33

Formula

C18H15N3O4
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Anxiolytic/nonsedative agent-1 相关分类

  • 摩尔计算器

  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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× = ×
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anxiolytic/nonsedative agent-1355022-97-8GABA ReceptorGamma-aminobutyric acid Receptorγ-Aminobutyric acid ReceptorHEK293 cellsanxioselectivenonsedativeγ-aminobutyric acid-A (GABAA)central benzodiazepine receptor (BzR)Inhibitorinhibitorinhibit

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