1. GPCR/G Protein Neuronal Signaling
  2. Cannabinoid Receptor
  3. Arachidonoyl-N,N-dimethyl amide

Arachidonoyl-N,N-dimethyl amide  (Synonyms: Arachidonic acid-N,N-dimethyl amide)

目录号: HY-134055
产品使用指南

Arachidonoyl-N,N-dimethyl amide (Arachidonic acid-N,N-dimethyl amide) 是一种内源性大麻素,可与中枢大麻素 (CB1) 和外周大麻素 (CB2) 受体结合。AEA 的生物作用通过细胞摄取和脂肪酸酰胺水解酶对酰胺键的水解而终止。花生四烯酸酰胺-N,N-二甲基酰胺是花生四烯酸酰胺的类似物,与人类中枢大麻素 (CB1) 受体 (Ki >1 μM) 结合较弱或不结合。浓度为 50 μM 时,可 100% 抑制大鼠神经胶质细胞间隙连接细胞间通讯。

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Arachidonoyl-N,N-dimethyl amide Chemical Structure

Arachidonoyl-N,N-dimethyl amide Chemical Structure

CAS No. : 45280-17-9

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生物活性

Anandamide (AEA) is an endogenous cannabinoid that binds to both central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors. The biological actions of AEA are terminated by cellular uptake and hydrolysis of the amide bond by the enzyme fatty acid amide hydrolase. Arachidonoyl-N,N-dimethyl amide is an analog of anandamide that exhibits weak or no binding to the human central cannabinoid (CB1) receptor (Ki >1 μM). It inhibits rat glial gap junction cell-cell communication 100% at a concentration of 50 μM.

分子量

331.54

Formula

C22H37NO

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Arachidonoyl-N,N-dimethyl amide 相关分类

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Arachidonoyl-N,N-dimethyl amide
目录号:
HY-134055
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