2. Neuronal Signaling
  3. Amyloid-β
  4. [Arg6]-β-Amyloid (1-40), england mutation

[Arg6]-β-Amyloid (1-40), england mutation 

目录号: HY-P5368
产品使用指南

摩尔计算器

[Arg6]-β-Amyloid (1-40), england mutation 是一种有生物活性的肽。(β淀粉样蛋白前体基因的几种突变会导致许多家族患常染色体显性阿尔茨海默病。其中，英语突变，即第 6 位的 His 被 Arg 取代，据报道可以加速寡聚体形成的动力学，寡聚体充当原纤维种子，对培养的神经元细胞具有更大的毒性。)

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Custom Peptide Synthesis

[Arg6]-β-Amyloid (1-40), england mutation Chemical Structure

[Arg6]-β-Amyloid (1-40), england mutation Chemical Structure

CAS No. : 1802084-26-9

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[Arg6]-β-Amyloid (1-40), england mutation 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

生物活性

[Arg6]-β-Amyloid (1-40), england mutation is a biological active peptide. (Several mutations in the beta amyloid precursor gene cause autosomal dominant Alzheimer's Disease in a number of kindreds. Among them, the English mutation, with His at position 6 replaced with Arg, was reported to accelerate the kinetics of oligomers formation which act as fibril seeds and are more toxic to cultured neuronal cells.)

分子量

4348.85

Formula

C194H300N54O58S
CAS 号
Sequence

Asp-Ala-Glu-Phe-Arg-Arg-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val
Sequence Shortening

DAEFRRDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

[Arg6]-β-Amyloid (1-40), england mutation 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

[Arg6]-β-Amyloid (1-40), england mutation1802084-26-9Amyloid-ββ-amyloid peptideAβAbetaInhibitorinhibitorinhibit

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