2. Neuronal Signaling
  3. Amyloid-β
  4. [Asn23] β-Amyloid (1-40), Iowa mutation

[Asn23] β-Amyloid (1-40), Iowa mutation 

目录号: HY-P5365
产品使用指南

摩尔计算器

[Asn23] β-Amyloid (1-40), Iowa mutation 是一种有生物活性的肽。(β淀粉样蛋白前体基因的几种突变会导致许多家族患常染色体显性阿尔茨海默病。爱荷华州突变（其中 Asp 23 被 Asn 取代）与严重的大脑淀粉样蛋白血管病 (CAA) 相关。受影响的个体在 APP 694 位上有一个错义突变。突变的 β-淀粉样肽聚集得更快，并形成有毒原纤维。)

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Custom Peptide Synthesis

[Asn23] β-Amyloid (1-40), Iowa mutation Chemical Structure

[Asn23] β-Amyloid (1-40), Iowa mutation Chemical Structure

CAS No. : 374796-72-2

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[Asn23] β-Amyloid (1-40), Iowa mutation 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

生物活性

[Asn23] β-Amyloid (1-40), Iowa mutation is a biological active peptide. (Several mutations in the beta amyloid precursor gene cause autosomal dominant Alzheimer's Disease in a number of kindreds. The Iowa mutation, where Asp 23 is replaced with Asn, is associated with severe cerebral amyloid beta-protein angiopathy (CAA). The affected individuals share a missense mutation in APP at position 694. The mutated beta-amyloid peptide aggregates more rapidly and forms toxic fibrils.)

分子量

4328.82

Formula

C194H296N54O57S
CAS 号
Sequence

Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asn-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val
Sequence Shortening

DAEFRHDSGYEVHHQKLVFFAENVGSNKGAIIGLMVGGVV
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

[Asn23] β-Amyloid (1-40), Iowa mutation 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

[Asn23] β-Amyloid (1-40), Iowa mutation374796-72-2Amyloid-ββ-amyloid peptideAβAbetaInhibitorinhibitorinhibit

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