2. Anti-infection
  3. SARS-CoV
  4. AT-9010

AT-9010 是 AT-527 的三磷酸活性代谢物，是一种有效的 NiRAN (病毒复制必不可少的功能) 的抑制剂。AT-9010 可以抑制 SARS-CoV-2 的复制。

在相同的摩尔浓度下，化合物盐形式与游离形式有相同的生物活性，但盐形式 AT-9010 tetrasodium 通常具有更好的水溶性和稳定性。

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AT-9010 Chemical Structure

AT-9010 Chemical Structure

CAS No. : 1261253-79-5

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规格 是否有货
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AT-9010 的其他形式现货产品:

Customer Review

Other Forms of AT-9010:

AT-9010 相关抗体

Top Publications Citing Use of Products

MCE 顾客使用本产品发表的 1 篇科研文献

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

AT-9010, a triphosphate active metabolite of AT-527, is a potent inhibitor of NiRAN (a function essential for viral replication). AT-9010 can inhibit SARS-CoV-2 replication[1].

IC50 & Target

NiRAN[1]
体外研究
(In Vitro)

Substantial levels of the active triphosphate metabolite AT-9010 are formed in normal human bronchial and nasal epithelial cells incubated with 10 µM AT-511 (698 µM and 236 µM, respectively), with a half-life of at least 38 hours[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

AT-9010 相关抗体:
分子量

539.20

Formula

C11H17FN5O13P3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

AT-9010 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AT-90101261253-79-5AT9010AT 9010SARS-CoVSARS coronavirustriphosphateAT-527NiRANSARS-CoV-2Inhibitorinhibitorinhibit

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目录号：
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