2. Cell Cycle/DNA Damage PI3K/Akt/mTOR
  3. ATM/ATR
  4. ATR-IN-5

ATR-IN-5 是一种有效的 ATR 抑制剂。ATR 是一类参与基因组稳定性和 DNA 损伤修复的蛋白激酶，是 PIKK 家族的成员。ATR-IN-5具有研究ATR激酶介导的疾病如增殖性疾病和癌症的潜力 (信息摘自专利CN112047938A，化合物D24)。

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ATR-IN-5 Chemical Structure

ATR-IN-5 Chemical Structure

CAS No. : 2601571-19-9

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ATR-IN-5 相关抗体

Top Publications Citing Use of Products

查看 ATM/ATR 亚型特异性产品:

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ATM ATR

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

ATR-IN-5 is a potent inhibitor of ATR. ATR is a class of protein kinases involved in genome stability and DNA damage repair, and is a member of the PIKK family. ATR-IN-5 has the potential for the research of ATR kinase-mediated diseases such as proliferative diseases and cancer (extracted from patent CN112047938A, compound D24)[1].

分子量

555.60

Formula

C27H32F3N9O
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

ATR-IN-5 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ATR-IN-52601571-19-9ATM/ATRAtaxia telangiectasia mutatedATM and RAD3 relatedgenome stabilityDNA damage repairPIKKproliferative diseasescancerInhibitorinhibitorinhibit

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目录号：
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