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  4. ATX inhibitor 17

ATX inhibitor 17 是一种有效的 ATX 抑制剂，IC50 为 0.019 µM。 ATX inhibitor 17 在乳腺癌细胞中显示出优异的抗增殖活性。

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ATX inhibitor 17 Chemical Structure

ATX inhibitor 17 Chemical Structure

CAS No. : 2750152-64-6

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ATX inhibitor 17 相关抗体

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  • 生物活性

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生物活性

ATX inhibitor 17 is a potent ATX inhibitor with an IC50 of 0.019 µM. ATX inhibitor 17 shows excellent anti-proliferative activities in breast cancer cells[1].

IC50 & Target

IC50: 0.019 µM (ATX)[1]
体外研究
(In Vitro)

ATX inhibitor 17 (compound 25a) (0-15 µM; 72 h) shows excellent anti-proliferative activities in breast cancer cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

ATX inhibitor 17 相关抗体:

Cell Cytotoxicity Assay[1]

Cell Line: MCF7, MDA-MB-231, A549, H2228 cells
Concentration: 0-15 µM
Incubation Time: 72 h
Result: Showed excellent antiproliferative effects with IC50s of 1.01, 0.79, 13.40, >15 µM for MCF7, MDA-MB-231, A549, H2228 cells, respectively.
分子量

616.65

Formula

C29H29F5N8S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

ATX inhibitor 17 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ATX inhibitor 172750152-64-6ATX inhibitor17ATX inhibitor-17Othersantitumorbreast cancerTrifluoroacetyl hydrazoneanti-proliferativeMCF7MDA-MB-231A549H2228Inhibitorinhibitorinhibit

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