2. Epigenetics
  3. Histone Acetyltransferase
  4. AUR1545

AUR1545 是一种选择性降解 KAT2A 和 KAT2B 的化合物。AUR1545 可用于癌症研究，包括对 AML、SCLC 和 NEPC 的研究。

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AUR1545 Chemical Structure

AUR1545 Chemical Structure

CAS No. : 3031593-79-7

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规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

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AUR1545 相关抗体

Top Publications Citing Use of Products

查看 Histone Acetyltransferase 亚型特异性产品:

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CBP/p300 GCN5/PCAF TIP60 MOZ/MORF HBO1

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

AUR1545 is a selective degrader of KAT2A and KAT2B. AUR1545 can be used in the cancer research, including studies on AML (Acute myeloid leukemia), SCLC (Small-cell carcinoma), and NEPC (Neuroendocrine Prostate Cancer)[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
LASCPC-01 DC50
0.16 nM
for KAT2B
for KAT2B
[1]
MOLM-13 DC50
0.11 nM
for KAT2A
for KAT2A
[1]
NCI-H1048 DC50
0.01 nM
for KAT2A
for KAT2A
[1]
MOLM-13 DC50
0.43 nM
for KAT2B
for KAT2B
[1]
NCI-H1048 DC50
0.04 nM
for KAT2B
for KAT2B
[1]
LASCPC-01 DC50
0.06 nM
for KAT2A
for KAT2A
[1]
分子量

828.80

Formula

C41H50BrN9O5
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

AUR1545 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AUR15453031593-79-7AUR 1545AUR-1545Histone AcetyltransferaseHATsHATKAT2AKAT2BAMLAcute myeloid leukemiaSCLCSmall-cell carcinomaNEPCNeuroendocrine Prostate CancerInhibitorinhibitorinhibit

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产品名称：
AUR1545
目录号：
HY-173158
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