2. Protein Tyrosine Kinase/RTK
  3. TAM Receptor c-Fms
  4. Axl/Mer/CSF1R-IN-1

Axl/Mer-IN-1 (Compound 1) 是一种 Axl/Mer 受体酪氨酸激酶 (Axl/Mer RTK) 和 CSF1R 抑制剂，Kd 值均小于 0.1 μM。

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Axl/Mer/CSF1R-IN-1 Chemical Structure

Axl/Mer/CSF1R-IN-1 Chemical Structure

CAS No. : 2394874-60-1

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Axl/Mer/CSF1R-IN-1 相关抗体

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Axl Mer Tyro3

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Axl/Mer-IN-1 (Compound 1) is an Axl/Mer receptor tyrosine kinase (Axl/Mer RTK) and CSF1R inhibitor with Kds of <0.1 μM[1].

IC50 & Target

Axl

 

Mer

 

体外研究
(In Vitro)

Axl/Mer-IN-1 (Compound 1) 抑制细胞 Axl 活性，通过 H1299 Elisa 法测得的IC50 为 <0.5 μM。Axl/Mer-IN-1 抑制细胞 CSF1R 活性，通过 THP-1 Elisa 法和 M-NFS-60 活力法测得的 IC50 分别为 <0.5 μM 和 <1.0 μM[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Axl/Mer/CSF1R-IN-1 相关抗体:
分子量

531.48

Formula

C25H24F3N5O5
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Axl/Mer/CSF1R-IN-1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Axl/Mer/CSF1R-IN-12394874-60-1TAM Receptorc-FmsTyro3AxlMerCSF-1 receptorcolony stimulating factor 1 receptorCSF-1RCSF1RTHP-1M-NFS-60H1299Inhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-153012
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