Azaline B 

Azaline B is an antagonist for gonadotropin-releasing hormone (GnRH) with IC₅₀ of 1.37 nM, Azaline B can be used in research of sex hormone-related pathological states, ovulation induction and male contraception^[1].

IC₅₀: 1.37 nM (GnRH)

1613.27

C₈₀H₁₀₂ClN₂₃O₁₂

134457-28-6

Ac-{d-Ala<2Nal>}-{d-Phe<Cl>}-{d-Ala<Py>}-Ser-{Phe<X>}-{d-Phe<X>}-Leu-{Lys<Ph>}-Pro-{d-Ala} X=3-amino-1H-1,2,4-triazol-5-yl)amino

Ac-{d-Ala<2Nal>}-{d-Phe<Cl>}-{d-Ala<Py>}-S-{Phe<X>}-{d-Phe<X>}-L-{Lys<Ph>}-P-{d-Ala} X=3-amino-1H-1,2,4-triazol-5-yl)amino

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Samant MP, et al., Novel gonadotropin-releasing hormone antagonists with substitutions at position 5. Biopolymers. 2005;80(2-3):386-91.  [Content Brief]